GLEOSTINE (LOMUSTINE) 10MG 5 CAPS (ONCOLOGY)

Gleostine® (lomustine) 10mg capsules are an oral chemotherapy medication used in oncology for the treatment of primary and metastatic brain tumors, including glioblastoma, as well as Hodgkin’s lymphoma, particularly in cases where the disease has progressed after initial chemotherapy. As an alkylating agent, lomustine interferes with the DNA and RNA of cancer cells, disrupting their replication process and ultimately causing cell death. It is typically administered as a single oral dose once every six weeks, with dosage carefully calculated based on the patient’s body surface area and clinical condition. Gleostine plays a critical role in managing aggressive central nervous system malignancies such as glioblastoma, one of the most challenging brain cancers to treat. Because of its high potency and delayed toxicity profile, it is dispensed in single-dose cycles to reduce the risk of overdose and cumulative toxicity. Common side effects may include nausea, vomiting, fatigue, and loss of appetite. More serious risks include delayed myelosuppression, which can lead to dangerously low blood cell counts and increase susceptibility to infection or bleeding. Routine monitoring of blood counts, liver function, and kidney function is essential throughout the treatment period. Due to the potential for significant side effects, Gleostine should only be used under the supervision of an experienced healthcare provider familiar with cancer chemotherapy protocols. This medication is a vital part of comprehensive treatment plans in oncology, particularly for patients with brain tumors and refractory hematologic malignancies.